- QUINAZOLINONE COMPOUNDS AND RELATED COMPOUNDS
-
Disclosed are substituted quinazolinone compounds, pharmaceutical compositions comprising such compounds, and methods of using such compounds and compositions to treat diseases, disorders, or conditions such as those relating to unregulated protein functi
- -
-
Paragraph 0167
(2021/08/27)
-
- TRICYCLIC DEGRADERS OF IKAROS AND AIOLOS
-
Tricyclic cereblon binders for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway for therapeutic applications are described.
- -
-
Page/Page column 542-543
(2020/10/21)
-
- Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
-
The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, and other diseases and conditions that are mediated by excessive glucocorticoid action.
- -
-
Page/Page column 57
(2008/06/13)
-
- IMIDAZO[1,2-A]PYRIDINES FOR THE TREATMENT OF CNS AND CARDIAC DISEASES
-
The present invention relates to imidazo[1,2-a]pyridine compounds of formula (1) STR1 which are dopamine D-4 antagonists and useful as anti-psychotic agents.
- -
-
-