A novel class of cationic and non-peptidic small molecules as hits for the development of antimicrobial agents
Cationic and non-peptide small molecules containing a total of six positive charges arranged on one side and a long aliphatic tail on the other have been synthesized and tested against Gram-positive and Gram-negative bacteria. The positive charges have be
Jiménez, Aranza,García, Pablo,De La Puente, Sofia,Madrona, Andrés,Camarasa, María José,Pérez-Pérez, María-Jesús,Quintela, José-Carlos,García-del Portillo, Francisco,San-Félix, Ana
(2018/07/10)
Head group analogs of arachidonylethanolamide, the endogenous cannabinoid ligand
Several analogs of an endogenous cannabimimetic, arachidonylethanolamide (anandamide), were synthesized to study the structural requirements of the ethanolamide head group. CB1 receptor affinities of the analogs were evaluated by a standard receptor bindi
Khanolkar, Atmaram D.,Abadji, Vasiliki,Lin, Sonyuan,Hill, W. Adam G.,Taha, Gihan,Abouzid, Khaled,Meng, Zhaoxing,Fan, Pusheng,Makriyannis, Alexandros
p. 4515 - 4519
(2007/10/03)
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