cas 186593-53-3, 2-AMINO-3-BROMO-5-HYDROXYPYRIDINE

A series of 3-pyrrolidinyloxy-3′-pyridyl ether compounds, a method for selectively controlling neurotransmitter release in mammals using these compounds, and pharmaceutical compositions including these compounds. Preferred compounds are 3-pyrrolidinylmethoxy-3′-(5′-and/or 6′-substituted) pyridyl ethers.

The present invention relates to a method of controlling pain in mammals, including humans, comprising administering to a mammal or patient in need of treatment thereof selected compounds of formula I: STR1 or a pharmaceutically acceptable salt thereof. The invention further relates to selected (R) and (S) compounds of formula I above which are useful as analgesics as well as neuronal cell death preventors and anti-inflammatories.

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Article Database

186593-53-3

Articles about 186593-53-3Total 5 be found

Chemical Properties

Boiling Point: 424.3 °C at 760 mmHg

Flash Point:210.4 °C

Density: 1.898 g/cm³

Storage Temp.:2-8°C

Vapor Pressure: 8.43E-08mmHg at 25°C

Refractive Index: 1.692

PKA: 9.69±0.10(Predicted)

PSA: 59.14000

LogP: 1.71310

Global suppliers and manufacturers of 186593-53-3total 22 suppliers on LookChem

Article Database

186593-53-3

Articles about 186593-53-3Total 5 be found

Chemical Properties

Boiling Point: 424.3 °C at 760 mmHg

Flash Point:210.4 °C

Density: 1.898 g/cm3

Storage Temp.:2-8°C

Vapor Pressure: 8.43E-08mmHg at 25°C

Refractive Index: 1.692

PKA: 9.69±0.10(Predicted)

PSA: 59.14000

LogP: 1.71310

Global suppliers and manufacturers of 186593-53-3total 22 suppliers on LookChem

Density: 1.898 g/cm³