- 1,3,8-TRIAZA- AND 3,8-DIAZA-1-OXASPIRO[4,5] DECANE DERIVATIVES
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Heterocyclic compounds of Formula I: STR1 in which n is 2, 3, 4, 5 or 6; t is 1, 2, 3 or 4; u is 0 or 1 (provided that t is not 1 when u is 0); X is O or N(R 4); Y and Z are independently C(O), C(S) or CH 2 (provided that Y and Z are not both CH 2); R 1, R. sup.2, R 3, and R 4 are as defined in the specification; and their pharmaceutically acceptable salts and N-oxides, formulations containing them, their uses as therapeutic agents, and their synthesis.
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