Synthesis of benzo[d]-1,2-thiazole-1,1-dioxide derivatives via directed lithiation of 2,2-dimethyl-N-(phenylsulfonyl)-propanamides
A novel synthesis of 7-substituted benzo[d]-1,2-thiazole-1,1-dioxides 4 is presented including directed lithiation of 2,2-dimethyl-N-(phenylsulfonyl)-propanamides 1 - 3, aryne-mediated cyclization and subsequent quenching of aryllithium intermediates with
Stanetty, Peter,Krumpak, Barbara,Emerschitz, Thomas,Mereiter, Kurt
p. 3615 - 3626
(2007/10/03)
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