Synthesis and evaluation of antitumor activity of arylamides and cyclohexylamides of isomeric 3-chloro-4-(2-chloroethylthio)butanoic- and 4-chloro-3-(2-chloroethylthio)butanoic acids
In the hope to find antitumor candidates among di-(2-chloroethyl)sulfides it was found that only 3-chloro-4-(2-chloroethylthio)butanoic (3-chloro) and 4-chloro-3-(2-chloroethylthio)butanoic (4-chloro) acids possess definite alkylating ability which is sug