Sulfoxide-containing aromatic nitrogen mustards as hypoxia-directed bioreductive cytotoxins
A series of diaryl and alkylaryl sulfoxide-containing nitrogen mustards were synthesized and evaluated for their hypoxia-selective cytotoxicity against V-79 cells in vitro as well as for their metabolism profiles with the rat S-9 fractions. In general, th
Sun,Botros,Su,Kim,Wang,Baturay,Kwon
p. 4160 - 4168
(2007/10/03)
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