Aryltricyclospirodienones; novel steroid mimics as inhibitors of aromatase
The aryltricyclospirodienones 16a, 16b, 16c and 18 have been designed as potential inhibitors of aromatase and are synthesised from 6-methoxytetralone; ? compounds 16a and 18 have proved effective inhibitors with activities of the same order as aminoglutethimide.
Hobbs-Mallyon, David,Li, Warren,Whiting, Donald A.
p. 1511 - 1516
(2007/10/03)
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