- Synthesis, biological evaluation and molecular modelling studies of novel ACD- and ABD-ring steroidomimetics as inhibitors of CYP17
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Two novel classes of non-steroidal substrate mimetics were synthesised and examined for their potency as inhibitors of human CYP17. Selected compounds were tested for inhibition of hepatic CYP enzymes 3A4, 1A2, 2C9 and 2C19. The most promising compound 15
- Pinto-Bazurco Mendieta, Mariano A.E.,Negri, Matthias,Jagusch, Carsten,Hille, Ulrike E.,Mueller-Vieira, Ursula,Schmidt, Dirk,Hansen, Klaus,Hartmann, Rolf W.
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p. 267 - 273
(2008/09/17)
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- NEW ANTHRACENE DERIVATIVES, PREPARATION METHOD THEREOF AND ORGANIC LIGHT EMITTING DIODE USING THE SAME
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The present invention provides a novel anthracene derivative, a method for preparing the same, and an organic electronic device using the same. The anthracene derivative according to the invention can function alone as a light emitting host, in particular, as a blue host in an organic electronic device. Further, the anthracene derivative according to the invention can also function as a hole injecting or hole transporting material, an electron injecting or electron transporting material, or a light emitting material in an organic electronic device including a light emitting device. Therefore, the organic electronic device according to the present invention shows excellent characteristics in efficiency, drive voltage and stability.
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Page/Page column 76-77
(2010/11/28)
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