Nonpeptide angiotensin II receptor antagonists: Synthesis and biological activity of 1H-Imidazo and 1H-[1,2,3]-Triazolo fused derivatives
A series of 1H-Imidazo and 1H-[1,2,3]-Triazolo fused derivatives have been obtained and tested as non peptide AII receptor antagonists. Modification of the classical biphenyl moiety to a 4-arylthienyl fragment afforded interesting activities.