- N-Alkylation of 4-Chloro-5-cyano-1,2,3-triazole with Orthoformic Acid Derivatives
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The N-alkylation of 4-chloro-5-cyano-1,2,3-triazole with methyl and ethyl orthoformate, and the dimethyl, diethyl and ethylene acetals of DMF has been examined.Methylation gives all three N-methyl isomers, whereas ethylation and hydroxyethylation gives 2-N-alkyl derivatives only.It has been shown for the first time that it is possible to use DMF ethylene acetal to obtain N-hydroxyethylazoles.The structure of the products were established by 13C NMR spectroscopy.
- Bulychev, Yu. N.,Preobrazhenskaya, M. N.,Chernyshev, A. I.,Esipov, S. E.
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- Synthesis of the new types of N-substituted aminomethylenebisorganophosphorus acids and their derivatives
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The interaction of esters of trivalent organophosphorus acids containing PH and POSiMe3 fragments with various derivatives of formamide is proposed as convenient methods for the synthesis of new N-substituted aminomethylenebisorganophos-phorus acids and their derivatives with three-, four-, and five-coordinated phosphorus. Also the new functionalized derivatives of the new aminomethylenebisphosphinic acids with substituted hydroxymethyl moieties are synthesized, and some properties of the obtained compounds are presented.
- Prishchenko, Andrey A.,Livantsov, Mikhail V.,Novikova, Olga P.,Livantsova, Ludmila I.,Petrosyan, Valery S.
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experimental part
p. 319 - 324
(2010/08/05)
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- NEW TYPES OF AMINOMETHYL ORGANOPHOSPHORUS COMPOUNDS
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We studied aminomethylation of various PH acids their derivatives containing highly reactive PH, PSi, POSi and PC(O) fragments: tris(trimethylsilyl)phosphine, trimethylsilyl esters of phosphorus(III) acids, pivaloylphosphonite, and hydrospirophosphoranes.Chloro-, alkoxy- or dialkylaminomethylamines, dialkylformamide acetals, azomethines, and enamines were used as aminomethylating reagents.Convenient methods for synthesizing previously unknown or difficult-to-obtain organic compounds of two-, three-, four, and five-coordinate phosphorus containing a P-C-N fragment were proposed.
- Prishchenko, A.A.,Livantsov, M.V.,Petrosyan, V.S.
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p. 1181 - 1193
(2007/10/02)
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