Design, synthesis, and biochemical evaluation of phosphonate and phosphonamidate analogs of glutathionylspermidine as inhibitors of glutathionylspermidine synthetase/amidase from Escherichia coli
Three phosphapeptides designed to mimic two distinct tetrahedral intermediates formed during either the synthesis or hydrolysis of glutathionylspermidine (Gsp) were synthesized and evaluated as inhibitors of the bifunctional enzyme Gsp synthetase/amidase.
Chen, Shoujun,Lin, Chun-Hung,Kwon, David S.,Walsh, Christopher T.,Coward, James K.
p. 3842 - 3850
(2007/10/03)
More Articles about upstream products of 197971-44-1