- XtalFluor-E mediated proto-functionalization of: N -vinyl amides: Access to N -acetyl N, O -acetals
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XtalFluor-E has been extensively used in a broad range of reactions in the past few years. Here we report its use with protic nucleophiles in a catalytic manner for the in situ generation of protons that lead to the proto-functionalization of activated ol
- Yi,Gholami,Morrow,Borhan
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supporting information
p. 9570 - 9574
(2017/11/30)
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- Process for producing pyrrolidone derivative
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Disclosed herein is a process for producing a pyrrolidone derivative represent by the general formula (I): STR1 wherein R is an organic residue obtained by removing hydroxy radical from a C1-10 primary alcohol, C1-10 secondary alcohol or derivative thereof, comprising (1) reacting 2-pyrrolidone with acetaldehyde in the presence of a catalyst, thereby obtaining N-(α-hydroxyethyl)pyrrolidone, and (2) reacting the thus obtained N-(α-hydroxyethyl)pyrrolidone with a primary alcohol, a secondary alcohol or a derivative thereof in the presence of an acidic catalyst to obtain the pyrrolidone derivative.
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- Organic Gas-Solid Reactions with Stilbenes, Chalcones, and Enamides
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Crystalline stilbene (1) adds gaseous chlorine and bromine without intermediate melting.The stereoselectivity is similar to that observed in solutions.Triphenylethene (3) also yields the products 4 in gas-solid reactions with chlorine and bromine, but these products tend to loose HX from the crystal; their conversion products are described.Neither crystalline 1 nor 3, but (E)-1,2-diphenyl-1-propene (7) adds gaseous hydrogen bromide regiospecifically.The same is true for the crystalline chalcone 10, which adds hydrogen bromide and -chloride selectively to give 11 nonisotypically.Gaseous ammonia reconverts crystalline 11 into 10.The enamide 12 in its crystalline state adds the gases hydrogen bromide, -chloride, methanethiol and hydrogen, to give the products 13, but also 15 (addition and condensation) and 16 (double addition). 13f which is formed via hydrogenation of crystals is not isotypical with its precursor 12.The liquid 17 crstallizes on freezing and then easily adds the gases hydrogen bromide (> - 50 deg C) and hydrogen chloride (> - 80 deg C) in highly controlled reactions to give the reactive compounds 18.These are converted not only into oligomers but also into the derivatives 19, 20, 21, and 22.The advantages of the unusual reaction procedures are discussed.
- Kaupp, Gerd,Matthies, Doris
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p. 1897 - 1904
(2007/10/02)
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- Process for the preparation of N-α-alkoxyalkyl-carboxamides, and some representatives of this class of compounds and secondary products obtained therefrom
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N-α-Alkoxyalkyl-carboxamides are prepared by reacting primary or secondary amides of aliphatic, araliphatic or aromatic carboxylic acids, or cyclic carboxamides (lactams) which are not capable of forming an aromatic system, with open-chain α-halogenoalkyl
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