cas 199339-71-4, 4-hydroxy-benzo[b]thiophene-7-carboxaldehyde | Articles data ｜lookchem

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199339-71-4

Articles about 199339-71-4Total 5 be found

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Isothiazole derivatives as GPR120 agonists for the treatment of type II diabetes
Disclosed are compounds, compositions and methods for treating of disorders that are affected by the modulation of the GPR120 receptor. Such compounds are represented by Formula (I) as follows: wherein R1, G, and Q are defined herein.
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Page/Page column 88; 89

(2015/07/07)

ISOTHIAZOLE DERIVATIVES AS GPR120 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES
Disclosed are compounds, compositions and methods for treating of disorders that are affected by the modulation of the GPR120 receptor. Such compounds are represented by Formula (I) as follows: wherein R1, G, and Q are defined herein.
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Page/Page column 104-105

(2015/11/02)

GPR120 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES
Disclosed are compounds, compositions and methods for treating of disorders that are affected by the modulation of the GPR120 receptor. Such compounds are represented by Formula (I) and Formula (II) as follows: wherein Y, R1, G, and Q are defined herein; and wherein R11, R21, R41, RB1 and G1, are defined herein.
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Paragraph 0858; 0859

(2014/09/30)

Process for the production of chiral propionic acid derivatives
The present invention is concerned with a novel process for the preparation of compounds of formula I comprising catalytic asymmetric hydrogenation of a compound of formula (II) in the presence of a catalyst comprising ruthenium and a chiral diphosphine ligand or comprising rhodium and a chiral diphosphine ligand, wherein R1, R2, R3 and R4 are as defined in the specification and claims. The compounds of formula I and the corresponding salts and/or esters are pharmaceutically active substances.
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Page/Page column 13

(2010/02/11)

Novel process for the preparation of the insulin sensitizer
A novel process for the preparation of compounds of formula I and optionally converting a compound of formula I into a pharmaceutically acceptable salt is disclosed. The compounds of formula I and the corresponding salts, e.g. the sodium salts, are pharma
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Page 6

(2010/02/10)

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Chemical Properties

Boiling Point: 372.8 °C at 760 mmHg
Flash Point:179.2 °C
Density: 1.447 g/cm³
PKA: 6.48±0.40(Predicted)
PSA: 65.54000
LogP: 2.41940

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