Reaction des vinylogues d'hemiacetals avec les ethers d'enols β-heterosubstitues : nouvelle synthese et cyclisation de composes δ-dicarbonyles α-heterosubstitues
Reaction of hemiacetal vinylogs 1 in the presence of boron trifluoride etherate with silyl enol ethers 2 or 3 prepared from α-heterosubstituted ketones 7 or 9 yields α-halo δ-dicarbonyl compounds 4 (X = Cl, Br) or α-methoxy δ-dicarbonyl compounds 5.When s
Poirier, Jean-Marie,Hennequin, Laurent,Fomani, Marie
p. 436 - 448
(2007/10/02)
SYNTHESE DE COMPOSES DICARBONYLES-1,5 α-HALOGENES UTILISANT DES VINYLOGUES D'HEMIACETALS VOIE D'ACCES A DES CYCLOPROPANES DISUBSTITUES-1,2
Reaction of hemiacetal vinylogs 1 with β-halo silyl enol ethers 2 in the presence of boron trifluoride etherate yields α-halo 1,5-dicarbonyl compounds 3 .Functionalized cyclopropanes 4 are obtained by reaction of diketones 3 in ethanolic potassium hydroxi