Preparation of 4-substituted-2-buten-4-olides from mucohalic acids
Methods and materials for preparing 4-substituted-2-buten-4-olides are disclosed. The method includes reacting a mucohalic acid with a silyl enol ether or a ketene silyl acetal in the presence of a Lewis acid.
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Page/Page column 10
(2010/02/15)
Mucohalic acid in Lewis acid catalyzed Mukaiyama aldol reaction: A concise method for highly functionalized γ-substituted γ-butenolides
The first Mukaiyama aldol reaction on mucohalic acid (1a/b) has been achieved. Reaction of 1 with various ketene silyl acetals or silyl enol ethers in the presence of a Lewis acid provides the γ-substituted γ-butenolides in good to excellent yield.
Angell, Paul,Zhang, Ji,Belmont, Daniel,Curran, Timothy,Davidson, James G.
p. 2029 - 2032
(2007/10/03)
SYNTHESE D'ENONES CYCLIQUES ET D'ACIDES DIENIQUES PAR REACTION DE WITTIG HORNER EMMONS
Enol lactones react with methyl diethylphosphonacetate to give directly cyclic 2-en 1-ones with a carbomethoxy substituent in the 2 position, while 5-OH 2(5H) furanones afford stereospecifically Z,E-dienic acids.
Canevet, J. C.,Sharrard, F.
p. 181 - 184
(2007/10/02)
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