The preparation of enantiomerically pure cyclopropylalanine
Single enantiomer cyclopropylalanine (>99.9% ee) and various derivatives were prepared using an asymmetric hydrogenation approach with a rhodium catalyst based on the methyl BoPhoz ligand. N-Boc cyclopropylalanine benzyl ester was the preferred derivative
Boaz, Neil W.,Debenham, Sheryl D.,Large, Shannon E.,Moore, Mary K.