cas 20098-20-8, 5-BROMO-2-ADAMANTANONE | Articles data

Articles about 20098-20-8Total 5 be found

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Adamantane sulfone and sulfonamide 11-β-HSD1 Inhibitors
Potent and selective adamantane sulfone and sulfonamide inhibitors of 11-β-HSD-1 have been discovered. Selected compounds from these series have robust pharmacokinetic profiles and strongly inhibit liver, fat, and brain HSD1 for extended periods after ora
Sorensen, Bryan,Winn, Martin,Rohde, Jeff,Shuai, Qi,Wang, Jiahong,Fung, Steven,Monzon, Katina,Chiou, William,Stolarik, DeAnne,Imade, Hovis,Pan, Liping,Deng, Xiaoqing,Chovan, Linda,Longenecker, Kenton,Judge, Russell,Qin, Wenying,Brune, Michael,Camp, Heidi,Frevert, Ernst U.,Jacobson, Peer,Link
p. 527 - 532
(2007)
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Bromination of adamantane and its derivatives with tetrabromomethane catalyzed by iron compounds
Catalytic bromination of adamantane and its derivatives with tetrabromomethane catalyzed by iron compounds has been performed. The favorable ratio of catalyst and reagents and the conditions of a selective synthesis of bromine-substituted adamantanes have been developed.
Khusnutdinov,Shchadneva,Khisamova
p. 184 - 187
(2015/04/14)

Structure-reactivity relationships: reactions of a 5-substituted aziadamantane in a resorcin[4]arene-based cavitand
(Figure presented) The complexatlon properties of two novel C5-substituted adamantanediazirines within the resorcin[4]arene-based cavitand 4 were investigated In DMSO-d6, revealing that binding Is up to 1.4 kcal/mol stronger for halogenated adamantanediazirines when compared with the unsubstituted species. The thermal behavior of 5-bromo-2-aziadamantane (3) was investigated by DSC analysis as the first representative of the adamantanediazirine family In the neat solid state, as well as encapsulated within the aromatic cavity of cavitand 4. In the solid phase, the reactions of photolytically or thermolytically generated 5-bromo-2-adamantanylldene (11) can be controlled by complexation within cavitand 4.
Wagner, Gerald,Knoll, Wolfgang,Bobek, Michael M.,Brecker, Lothar,Van Herwijnen, Hendrikus W. G.,Brinker, Udo H.
supporting information; experimental part
p. 332 - 335
(2010/03/25)

INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME
The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatme
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Page/Page column 87

(2008/06/13)

Reversal of diastereoselectivities in intra- and intermolecular reactions of 2-adamantanylidenes primarily caused by electron-donating and electron-withdrawing substituents on C5
(Matrix presented) A reversal of diastereoselectivity was observed for novel 5-(trimethylsilyl)adamantan-2-ylidene (1c) with regard to 5-hydroxyadamantan-2-ylidene (1a). Ostensibly in intermolecular reactions, 5-substituted 2-adamantanylidenes (1) are ste
Knoll, Wolfgang,Bobek, Michael M.,Kalchhauser, Hermann,Rosenberg, Murray G.,Brinker, Udo H.
p. 2943 - 2946
(2007/10/03)

Chemical Properties

Melting Point: 153 °C
Boiling Point: 295.3 °C at 760 mmHg
Flash Point:88.4 °C
Density: 1.579 g/cm³
Vapor Pressure: 0.00154mmHg at 25°C
Refractive Index: 1.606
PSA: 17.07000
LogP: 2.52910

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Chemical Properties

Melting Point: 153 °C

Boiling Point: 295.3 °C at 760 mmHg

Flash Point:88.4 °C

Density: 1.579 g/cm³

Vapor Pressure: 0.00154mmHg at 25°C

Refractive Index: 1.606

PSA: 17.07000

LogP: 2.52910

Global suppliers and manufacturers of 20098-20-8total 27 suppliers on LookChem

Article Database

20098-20-8

Articles about 20098-20-8Total 5 be found

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Chemical Properties

Melting Point: 153 °C

Boiling Point: 295.3 °C at 760 mmHg

Flash Point:88.4 °C

Density: 1.579 g/cm3

Vapor Pressure: 0.00154mmHg at 25°C

Refractive Index: 1.606

PSA: 17.07000

LogP: 2.52910

Global suppliers and manufacturers of 20098-20-8total 27 suppliers on LookChem

Density: 1.579 g/cm³