Synthesis of 4-alkyl-1,2-diphenyl-3,5-dioxopyrazolidines possessing aryl methylsulfonyl and sulfonamide pharmacophores for evaluation as selective cyclooxygenase-2 (COX-2) inhibitors
A group of 1,2-diphenyl-3,5-dioxopyrazolidines possessing a methylsulfonyl (11) or sulfonamide (15) substituent at the para position of the N1-phenyl ring, in conjunction with a hydrogen, methyl or fluoro substituent at the para position of the
Rahim, M. Abdur,Rao, P.N. Praveen,Knaus, Edward E.
p. 1309 - 1314
(2007/10/03)
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