- Synthesis of β-trifluoroacetyl-substituted vinyl sulfones and vinyl sulfides
-
Oxidation of β-(trifluoroacetyl)vinyl sulfides afforded a series of the corresponding sulfones. The reactions of sulfones with various alkyl- and arylthiols were studied. These reactions provide the basis for a new procedure for the synthesis of β-(trifluoroacetyl)vinyl sulfides.
- Krasovsky,Nenajdenko,Balenkova
-
p. 2080 - 2085
(2007/10/03)
-
- A novel efficient synthesis of heteroaryl substituted α,β-unsaturated trifluoromethyl ketones
-
A synthesis of a novel electrophilic reagent 1,1,1-trifluoro-4-(phenylsulfonyl)-but-3-ene-2,2-diol 2 is described. The reaction of 2 with various electron-rich heteroaromatics such as furans, pyrroles, indoles is investigated. The addition-elimination reaction proceeds under mild conditions stereospecifically and permits a novel one-step procedure for the preparation of trifluoroacetylvinyl substituted heterocycles in high yield. In all cases only E-isomers of unsaturated CF3 ketones were obtained.
- Nenajdenko, Valentine G.,Krasovsky, Arkady L.,Lebedev, Mikhail V.,Balenkova, Elizabeth S.
-
p. 1349 - 1350
(2007/10/03)
-