- Process for the preparation of N,N'-disubstituted guanidines
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A process for the preparation of aromatic N,N'-disubstituted guanidines is described in which the corresponding aromatic N,N'-disubstituted thioureas are reacted with ammonia and oxygen or with an oxygen-containing gas, in the presence of a solvent and el
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- Process for isolating diarylguanidines
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Diarylguanidines can be isolated from the crude melt from the reaction of arylamines and cyanogen chloride in excellent quality and yield by dissolving the hot melt in water, extracting this solution with at least one polar, water-insoluble, organic compound, and precipitating from the purified aqueous solution the diarylguanidine by adding alkali metal hydroxide.
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- Process for producing N-phosphonomethylglycine acid
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The invention provides a process for producing N-phosphonomethylglycine acid (NPMG) comprising (a) oxidizing an N-(phosphonomethyl) iminodiacetic acid (NPMIDA) derivative of the general formula I STR1 wherein n is 1 or 2 and R5, R5', R6 and R6' are independently H, NH2, STR2 or an aryl, cycloalkyl or straight or branched chain alkyl or alkenyl group optionally substituted by hydroxy or halogen, or an alkylaryl group, provided that at least one of R5, R5 ', R6 or R6 ' is hydrogen, to produce a corresponding iminourea salt of NPMG and then (b) reacting the salt with an acid stronger than NPMG whereby NPMG is produced and there remains in solution the iminourea salt of the stronger acid.
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