CHOLECYSTOKININ 2 RECEPTOR TARGETED NIR IMAGING AND USE THEREOF
Compounds are described herein where CCK2R targeting ligands are attached to an imaging agent through a linker. The compounds can be used in the detection, diagnosis, imaging and treatment of cancer.
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(2018/04/20)
CCK2R-DRUG CONJUGATES
The disclosure provided herein pertains to CCK2R-drug conjugates. In particular, the disclosure pertains to CCK2R-drug conjugates that target the delivery of drugs to a mammalian recipient. Also described are methods of making and using CCK2R-drug conjuga
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Paragraph 0452; 0463; 0464
(2017/03/14)
CHOLECYSTOKININ B RECEPTOR TARGETING FOR IMAGING AND THERAPY
Conjugates are described herein where CCK2R targeting ligands are attached to an active moiety, such as therapeutic agent or an imaging agent, through a linker. The conjugates can be used in the detection, diagnosis, imaging and treatment of cancer.
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(2013/09/12)
METHOD FOR MANUFACTURING 1,5-BENZODIAZEPINE DERIVATIVE
An industrially advantageous method for producing a 1,5-benzodiazepine compound is provided. A compound (5) is obtained according to the reaction scheme shown below, and this compound is used as an intermediate.
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(2012/01/15)
Calcium salts of 1,5-benzodiazepine derivatives, process for producing the salts and drugs containing the same
Provided are calcium salts of a 1,5-benzodiazepine derivative represented by the following formula (I): (wherein, R1 represents a lower alkyl group, R2 represents a phenyl or cyclohexyl group, and Y represents a single bond or a lowe
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(2008/06/13)
1,5 Benzodiazepine derivatives
1,5-Benzodiazepine derivatives represented by formula (I), salts thereof, and medicines containing the same as the active ingredient: The compounds exhibit excellent gastrin and/or CCK-B receptor antagonism and are useful as remedies for gastric ulcer and gastrointestinal movement disorder.
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(2008/06/13)
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