- REACTION OF 2-SUBSTITUTED 5,5-DIMETHYL-4-OXO-1-PYRROLINE-1-OXIDES WITH NUCLEOPHILIC REAGENTS AND SYNTHESIS OF NITROXYL RADICALS - DERIVATIVES OF PYRROLIDINE
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The reaction of β-oxonitrones, derivatives of pyrroline, with nitrogeneous nucleophiles and NaBH4 proceeds at the carbonyl group with the retention of the nitrone group.The reaction with organomagnesium and organolithium compounds takes place at the nitro
- Reznikov, V. A.,Volodarskii, L. B.
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p. 329 - 334
(2007/10/02)
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- INFLUENCE OF CHEMICAL STRUCTURE OF NITROXYL SPIN LABELS ON THEIR REDUCTION BY ASCORBIC ACID
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The influence of structure on the reduction of nitroxyl spin labels by ascorbic acid was examined using both piperidine and pyrrolidine nitroxyls.A five-fold molar excess of ascorbic acid and pH of 7.4 were used.The nitroxyl concentration was measured by electron spin resonance spectrometry.The five-membered (pyrrolidine) nitroxyls were more stable than the six-membered derivatives.Ring substituents also influenced the reaction.The anionic derivatives were more stable than the unionized compounds which, in turn, were more stable than the amines (cations at pH 7.4).
- Couet, W. R.,Brasch, R. C.,Sosnovsky, G.,Lukszo, J.,Prakash, I.,et. al.
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p. 1165 - 1172
(2007/10/02)
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- Nitroxydes 99: β-Cetoaldehydes nitroxydes et chelates metalliques correspondants a structure rigide. Synthese et etude spectroscopique
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Syntheses and spectroscopic study of β-ketoaldehyde nitroxides and corresponding metal chelates (Copper II, Palladium II, and vanadyl) are described.The diamagnetic or paramagnetic nature of the complexed metal explains the various ESR spectra observed.A new route to 2,2,5,5-tetramethylpyrrolidin-3-one-1-yloxy, a nitroxide scarcely used so far in spite of its potentialities, is also described.
- Espi, Jean-Claude,Ramasseul, Rene,Rassat, Andre,Rey, Paul
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