- SULPHAMOYLPYRROLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B
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Inhibitors of HBV replication of Formula (A) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein Ra to Rd, and R5 to R6 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.
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Page/Page column 42
(2015/09/23)
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- SULPHAMOYLPYRROLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B
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Inhibitors of HBV replication of Formula (ID) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein X, Ra to Rd and R4 to R6 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.
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Page/Page column 82
(2014/12/12)
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- Synthesis and properties of 1-alkyl-2-methyl-3-sulfonylpyrroles and 1-alkyl-2-methyl-3-sulfonylpyrrole-5-carboxylic acid derivatives
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1,2-Dialkyl-3-sulfonylpyrroles are versatile synthetic tools for obtaining related fused ring heterocycles, for instance, pyrrolothiazines. We have established a method for obtaining pyrrolic compounds with a variety of 3-sulfonyl moieties such as sulfone
- Moranta, Concepcio,Molins-Pujol, Antoni M.,Pujol, M. Dolors,Bonal, Joaquim
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p. 3285 - 3291
(2007/10/03)
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