- First synthesis of L-ascorbic acid (vitamin C) from a non-carbohydrate source
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The enantiopure cis-1,2-dihydrocatechol 2, which is obtained by microbial oxidation of chlorobenzene, has been converted, via 3,5-O-benzylidene-L-gulonolactone (8), into L-ascorbic acid (1).
- Banwell, Martin,Blakey, Simon,Harfoot, Gwion,Longmore, Robert
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- Cis-1,2-Dihydrocatechols in chemical synthesis: First synthesis of L-ascorbic acid (vitamin C) from a non-carbohydrate source
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The cis-1,2-dihydrocatechol (2), which is obtained in enantiopure form by microbial oxidation of chlorobenzene, has been converted, via 3,5-O-benzylidene-L-gulono-1,4-lactone (8), into L-ascorbic acid (1).
- Banwell, Martin G.,Blakey, Simon,Harfoot, Gwion,Longmore, Robert W.
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p. 137 - 142
(2007/10/03)
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