- In search of imidazo [1,2-a] pyridine derivatives exhibiting resistance for catalytic hydrogenation
-
Effect of substituents on the pyridine ring of imidazo [1,2-a] pyridine derivatives have been studied to ascertain the structural requirement for offering resistance towards catalytic hydrogenation of the title compounds.
- Misra, Anju P.,Raj,Bhaduri
-
-
Read Online
- Imidazo[1,2-a]pyridin-2-ylacetic acid and two pairs of isomorphous ML 2(H2O)2 dihydrates (M = Ni, Co and Mn, Cd) based on its anion: Syntheses, crystal structures and properties
-
Imidazo[1,2-a]pyridin-2-ylacetic acid (HL, 1) and four ML 2(H2O)2·2H2O (M = Ni (2), Co (3), Mn (4), Cd (5)) complexes formed by its anion were synthesized, structurally characterized by single-crystal X-ray diffraction and investigated in terms of their thermal stability. In addition, magnetic properties of 2-4 are reported and the NIR-Vis-UV spectra of 2 and 3 are discussed in details. The crystal of 1 comprises 2D hydrogen bonded networks held in the crystal lattice by weak C-H.
- Dylong, Agnieszka,Sowa, Micha?,Goldeman, Waldemar,?lepokura, Katarzyna,Duczmal, Marek,Wojciechowska, Agnieszka,Matczak-Jon, Ewa
-
-
- NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A
-
The present invention relates to novel carboxamide compounds, pharmaceutical compositions containing them, and their use in therapy. The compounds possess valuable therapeutic properties and are particularly suitable for treating or controlling medical disorders selected from neurological disorders and psychiatric disorders, for ameliorating the symptoms associated with such disorders and for reducing the risk of such disorders
- -
-
-
- Synthesis of bridgehead nitrogen heterocycles on a solid surface
-
Bridgehead nitrogen heterocycles were synthesized from heteroaromatic amidines and cyclic or acyclic α-bromoketones under solvent-free conditions at room temperature on a solid surface in excellent yields, which are higher than those obtained with hithert
- Ponnala, Shashikanth,Kumar, S. T. V. S. Kiran,Bhat, Bashir A.,Sahu, Devi Prasad
-
p. 901 - 906
(2007/10/03)
-
- Heterocyclic compounds having anti-diabetic activity and their use
-
Compounds of formula (I): STR1 [wherein: X represents an unsubstituted or substituted indolyl, indolinyl, azaindolyl, azaindolinyl, imidazopyridyl or imidazopyrimidinyl group; Y represents an oxygen or sulfur atom; Z represents a 2,4-dioxothiazolidin-5-ylidenylmethyl, 2,4-dioxothiazolidin-5-ylmethyl, 2,4-dioxooxazolidin-5-ylmethyl, 3,5-dioxooxadiazolidin-2-ylmethyl or N-hydroxyureidomethyl group; R represents a hydrogen atom, an alkyl group, an alkoxy group, a halogen atom, a hydroxy group, a nitro group, an aralkyl group or a unsubstituted or substituted amino group; and m is an integer of from 1 to 5] have hypoglycemic and anti-diabetic activities.
- -
-
-