- Synthesis and alkylation of hexahydro-1,3,5-triazine-2-thione derivatives
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A series of new hexahydro-1,3,5-triazine-2-thione derivatives were prepared by aminomethylation of thiourea with formaldehyde and primary amines; with aniline as amine component, an abnormal aminomethylation product is formed, 5-phenyl-1-phenylaminomethylhexahydro-1,3,5-triazine-2-thione. Alkylation of 5-tert-butylhexahydro-1,3,5-triazine-2-thione with alkyl halides and with methyl and ethyl bromoacetate yields hydrohalides of 2-alkylthio- and 2-alkoxycarbonylmethylthio-5-tert-butyl-3,4,5,6-tetrahydro-1,3,5-triazines, respectively.
- Lazarev,Ramsh,Ivanenko
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p. 442 - 449
(2007/10/03)
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