- Synthesis and characterization of some novel copper(II) complexes with an optically active Betti base
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Novel Cu(II) complexes with racemic as well as optically pure 1-(α-amino benzyl)-2-napthol, commonly known as Betti base, and its derivative 1-(α-pyrrolidinyl benzyl)-2-napthol have been synthesized. The general composition of all the isolated complexes, as determined by elemental analysis, thermal analysis and FAB mass spectra, is found to be Cu(L-H) 2. The coordination of the ligand with metal has been confirmed by IR and ESR spectra of the complexes. The CD spectra of complexes with the S-form of the ligands exhibit a mirror image relationship with the CD spectra of the complexes with the corresponding R-form of the ligands. The Cu(II) complex with racemic Betti base has been characterized structurally. It crystallizes in the monoclinic space group P21/c. The complexes display quasi reversible redox behavior due to the Cu(II)/Cu(I) reduction process.
- Bhatt, Shardul,Trivedi, Bhavna
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scheme or table
p. 15 - 22
(2012/05/20)
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- Acid promoted CIDT for the deracemization of dihydrocinnamic aldehydes with Betti's base
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Racemic α-epimerizable and unfunctionalized aldehydes have been converted into enantiomerically enriched mixtures through a sequence of (i) a conversion into the diastereoisomeric 3-substituted 1-phenyl-2,3-dihydro-1H- naphtho[1,2-e][1,3]oxazines by reaction with the (R)- or (S)-1-(α- aminobenzyl)-2-naphthol (Betti's base), (ii) an acid promoted crystallization-induced diastereoisomer transformation (CIDT), and (iii) a clean cleavage of the dihydro-1,3-naphthoxazinic ring of the enriched diastereoisomer, easily collected by filtration, allowing the recovery of the enantiomerically enriched aldehydes and the chiral auxiliary.
- Rosini, Goffredo,Paolucci, Claudio,Boschi, Francesca,Marotta, Emanuela,Righi, Paolo,Tozzi, Francesco
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scheme or table
p. 1747 - 1757
(2011/02/28)
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- Phosphonylation of 1,3-diaryl-2,3-dihydro-1H-naphth[1,2-e][1,3]oxazine by dialkyl and diaryl phosphonates
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The possibility of using of easily available 1-(α-aminobenzyl)-2- naphthols as chiral auxiliaries in the synthesis of non-racemic α-aminophosphonates has been shown. Copyright Taylor & Francis Group, LLC.
- Metlushka, Kirill E.,Alfonsov, Vladimir A.,McKenna, Charles E.,Kashemirov, Boris A.,Kataeva, Olga N.,Zheltukhin, Viktor F.,Sadkova, Dilyara N.,Dobrynin, Alexey B.
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body text
p. 2645 - 2646
(2009/09/25)
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- A new approach to the enantioseparation of Betti bases
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An improved method for enantioseparation of racemic 1-(α-aminobenzyl) -2-naphthols has been developed by the reaction in situ of Betti base product mixtures with L-(+)-tartaric acid taken in a 1:1 ratio. The products of this reaction are (-)-1-(α-aminobenzyl)-2-naphthol tartrate, the acetal of benzaldehyde and tartaric acid as well as (+)-1,3-diaryl-2,3-dihydro-1H- naphth[1,2-e][1,3]oxazine, which can be easily separated by crystallization. Georg Thieme Verlag Stuttgart.
- Alfonsov, Vladimir A.,Metlushka, Kirill E.,McKenna, Charles E.,Kashemirov, Boris A.,Kataeva, Olga N.,Zheltukhin, Viktor F.,Sadkova, Dilyara N.,Dobrynin, Alexey B.
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p. 488 - 490
(2007/12/27)
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- An efficient kinetic resolution of racemic betti base based on an enantioselective N,O-deketalization
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An efficient kinetic resolution of racemic Betti base with L-(+)-tartaric acid in acetone was developed based on a novel enantioselective N,O-deketalization, by which the enantiopure R- and S-enantiomers of Betti base were obtained as the corresponding N,
- Dong, Yanmei,Li, Rui,Lu, Jun,Xu, Xuenong,Wang, Xinyan,Hu, Yuefei
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p. 8617 - 8620
(2007/10/03)
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