- Isopimarane diterpenoids from Aeollanthus rydingianus and their antimicrobial activity
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Four acyloxy-isopimarane derivatives along with two known isopimarane diterpenoids, the flavone cirsimaritin and the sterols β-sitosterol and stigmasterol were isolated from the aerial parts of Aeollanthus rydingianus. The structures of the compounds were
- Rijo, Patricia,Simoes, Maria Fatima,Duarte, Aida,Rodriguez, Benjamin
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- 2H N.M.R. Determination of the Stereochemistry of an Allylic Displacement in the Biosynthesis of Virescenol B
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Feeding of (5R)-mevalonate to Oospora virescens and 2H n.m.r. analysis of a derivative of the resulting virescenol B establish that the allylic displacement of pyrophosphate which generates ring c takes place with overall anti stereochemistry.
- Cane, David E.,Hasler, Heinz,Materna, Joan,Cagnoli-Bellavita, Nera,Ceccherelli, Paolo,et al.
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- Isopimarane diterpene glycosides, isolated from endophytic fungus Paraconiothyrium sp. MY-42
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Six isopimarane diterpenes, compounds 1-6, were isolated from the endophytic fungus Paraconiothyrium sp. MY-42. Compound 1 possesses a 19-glucopyranosyloxy group. Its structure was first elucidated by spectroscopic data analysis and finally confirmed by X-ray crystallography, whereas structures 2-6 were mainly elucidated based on the analysis of spectroscopic evidence. Compounds 2 and 3 showed moderate cytotoxicities against the human promyelocytic leukemia cell line HL60 (IC50 6.7 μM value for 2 and 9.8 μM for 3).
- Shiono, Yoshihito,Kikuchi, Miwako,Koseki, Takuya,Murayama, Tetsuya,Kwon, Eunsang,Aburai, Nobuhiro,Kimura, Ken-Ichi
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experimental part
p. 1400 - 1405
(2012/01/12)
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- New diterpenic altrosides of the fungus Acremonium striatisporum isolated from a sea cucumber
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Two new diterpenic glycosides, virescenosides M (1) and N (2), have been isolated from a marine strain of Acremonium striatisporum KMM 4401 associated with the holothurian Eupentacta fraudatrix. Their structures were determined on the basis of MS and NMR data as β-D-altropyranosido-19-7-oxo-isopimara- 8,15-diene-2α,3β-diol (1) and β-D-altropyranosido-19-isopimara-7,15-diene- 2α,3β,6β-triol (2). Three other altrosides (3-5), identified as virescenosides A, B, and C from the terrestrial strain Acremonium luzulae, were also isolated. The cytotoxic activity of the virescenosides was examined.
- Afiyatullov, Shamil Sh.,Kuznetsova, Tatyana A.,Isakov, Vladimir V.,Pivkin, Mikhail V.,Prokofeva, Nina G.,Elyakov, George B.
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p. 848 - 850
(2007/10/03)
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