- General synthesis of 4-aryloxy-6-methylpyrimidin-2-amines and their fragmentation under positive electrospray ionization
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A number of 4-aryloxy-6-methylpyrimidin-2-amines were synthesized by reaction of 2-amino-6-methylpyrimidin-4-yl 4-methylbenzenesulfonate with phenols. The main fragmentation pathway of these compounds under positive electrospray ionization is decomposition of the heterocycle.
- Erkin,Yuzikhin,Krutikov,Papinyan
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p. 1430 - 1433
(2015/11/25)
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- 5-HT2B RECEPTOR ANTAGONISTS
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Compounds of formulae: (I), (II), (IIIa), (IIIb), (IVa) and (IVb): or a pharmaceutically acceptable salt thereof, for use as pharmaceuticals, in particular for the treatment of a condition alleviated by antagonism of a 5-HT2B receptor.
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Page/Page column 79-80
(2008/06/13)
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