Methode simple de synthese de la 6H- benzopyranno quinoleine.
A facile synthesis of 6H- benzopyranno quinoline is achieved from propargyloxysalicylanilide (yield 72 percent).Reaction mechanism postulates the attack of triple bond by a nitrilium salt.
Rougeot, Par Etienne,Moskowitz, Henri,Miocque,Marcel
A novel strategy for the synthesis of 6H-chromeno [4, 3-b] quinoline by intramolecular Heck cyclization
A novel procedure for the synthesis of various derivatives of 6H-chromeno [4, 3-b] quinolines from intramolecular Heck reaction of 2-chloro-3-(phenoxymethyl) quinolines is described in this study. Intramolecular cyclization of N-alkylated indoles was efficiently investigated as well. The reaction is catalyzed by bis (triphenylphosphine) palladium (II) dichloride in acetonitrile at 80?°C.
Copper-catalyzed formal [3 + 3] annulations of arylketoximes and o-fluorobenzaldehydes: An entry to quinoline compounds
A copper-based catalytic system has been developed to enable efficient cyclization of ketoxime acetates with ofluorobenzaldehydes. This protocol offers an efficient method for the synthesis of substituted quinoline derivatives with a broad range of compatible functionalities. The present system also provides a rapid access to synthetically and pharmaceutically useful quinoline-fused polycycles such as benzo[c]acridines.
Copper-catalyzed intramolecular domino synthesis of 6H-chromeno[4,3-b]quinolines in green condition
A one-pot and efficient copper-catalyzed approach for synthesis of tetracyclic 6H-chromeno[4,3-b]quinolines through the intramolecular domino condensation-aza-Diels-Alder reaction of electron-rich anilines and Opropargylated salicylaldehydes under green conditions has been described.
Rahimzadeh, Golnaz,Soheilizad, Mehdi,Kianmehr, Ebrahim,Larijani, Bagher,Mahdavic, Mohammad
p. 20 - 28
(2018/06/27)
Copper-Catalyzed Aza-Diels-Alder Reaction and Halogenation: An Approach to Synthesize 7-Halogenated Chromenoquinolines
A new halogenation method to construct halogen-substituted quinoline moieties is described. The Cu-catalyzed intramolecular aza-Diels-Alder reaction and halogenation reaction proceeded smoothly under mild conditions to produce the corresponding 7-chloro-6H-chromeno[4,3-b]quinolines and 7-chloro-6H-thiochromeno[4,3-b]quinolines in satisfactory yields.
Yu, Xiaoqiang,Wang, Jiao,Xu, Zhanwei,Yamamoto, Yoshinori,Bao, Ming
supporting information
p. 2491 - 2494
(2016/06/09)
A flexible approach to the chromenoquinolines under copper/lewis acid catalysis
The synthesis of chromenoquinolines via cyclization of different substituted anilines or naphthylamine with O-propargylated salicylaldehydes using CuI/La(OTf)as an efficient catalyst in the reflux temperature of acetonitrile is reported. Georg Thieme Verlag Stuttgart ? New York.
Microwave assisted friedlander condensation catalyzed by clay
Clay catalyzed Friedlander condensation of 2-amino arylaldehyde or ketone with carbonyl compounds containing α-methylene group has been achieved in solvent free condition under microwave irradiation to give polycyclic quinoline derivatives.