- Novel organotin complexes derived from 2,2′-selenodiacetic acid: Synthesis and biological evaluation
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The reactions of 2,2′-selenodiacetic acid and the corresponding organotin(iv) chloride with sodium ethoxide in ethanol, or via a solvothermal synthetic route, have afforded four organotin polymers, namely, [(Me3Sn)2Se(CH2COO)2]n (1), [(Me2Sn)2Se(CH2COO)2(μ3-O)]n (2), [(Bu3Sn)2Se(CH2COO)2]n (3), and [(Bu2Sn)Se(CH2COO)2]n (4). All the complexes were fully characterized by elemental analysis, FT-IR, NMR (1H, 13C, and 119Sn) spectroscopy and single crystal X-ray diffraction analysis. The structural analysis reveals that complex 1 is a 2D-polymer containing interconnected 24-membered (Sn4O8C10Se2) macrocyclic rings. Unlike complex 1, the 2D polymer structure of complex 2 is made up of the typical ladder tetraorganodistannoxane unit containing 32-membered (Sn4O8C16Se4) macrocyclic rings. Complex 3 is a 3D corrugated polymeric structure in which the deprotonated dicarboxylic acid acts as a tetradentate ligand by four oxygen atoms. Complex 4 is a 1D zigzag coordination polymer and the tin coordination geometry is described as skewed-trapezoidal bipyramidal. In particular, preliminary cytotoxic assessments of the involvement of complex 4 in the apoptotic death of MDA cells were conducted, and the results revealed that the antiproliferative and proapoptotic effect of complex 4 in MDA cells prominently contributed to the overload of intracellular ROS levels and the dysfunctional depolarization of mitochondrial membranes.
- Li, Qianli,Liu, Xinglong,Cheng, Shuang,Zhang, Rufen,Shi, Yang,Ma, Chunlin
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- On the constituents of aqueous polyselenide electrolytes: A combined theoretical and Raman spectroscopic study
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The speciation of aqueous polyselenide solutions at high pH values has been investigated by Raman and UV/vis absorption spectroscopy. Complementary, ab initio molecular orbital calculations at the HF/6-31+G* level of theory have been carried out on the vibrational frequencies of polyselenide dianions Sex2- (x = 2-4), polyselenide radical anions Sex- (x = 2, 3), and protonated polyselenides HSex- (x = 1-3) in order to substantiate the assignment of the experimental Raman spectra. Although the optical spectra suggest the successive formation of Se22-, Se32-, and Se42- with progressive oxidation of the solutions, only two characteristic Raman bands are observed at 269 and 324 cm-1. A sequence of overtones of the 269 cm-1 band is observed after excitation with blue light. Likewise strong overtones of the 324 cm-1 band appear after excitation with green light. The 269 cm-1 feature is assigned to Se42- while the 324 cm-1 band is attributed to the radical anion Se2-. The occurrence of polyselenide radicals in aqueous solution is without precedent, and the formation of Se2- is ascribed to a photolytic process in the electrolyte. The only protonated species observed in this study is HSe-, which is characterized by a Raman band at 2303 cm-1.
- Goldbach,Johnson,Meisel,Curtiss,Saboungi, Marie-Louise
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- Electrochemical synthesis of organochalcogenides in aqueous medium
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The electrochemical preparation of telluride, selenide and sulfide ions was carried out in NaOH aqueous solution, using a two compartment cell. Organochalcogenides were prepared from halogenated compounds in a two-step procedure. The monochalcogenides were obtained as the major products in good yields.
- Ribeiro Neto, Pedro B.,Santana, Sonydelane O.,Levitre, Guillaume,Galdino, Danilo,Oliveira, Jadson L.,Ribeiro, Rogério T.,Barros, Maria E. S. B.,Bieber, Lothar W.,Menezes, Paulo H.,Navarro, Marcelo
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supporting information
p. 657 - 661
(2016/02/12)
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- Homo- and heteropolychalcogenide anions Ch2-, HCh-, Ch22-, Ch32-, and Ch42- (Ch = Se and/or Te): Solution 1H, 77Se, 123Te, and 12
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The homo- and heteropolychalcogenide anions, Chn2- (n = 1, 2, 3, 4; Ch = Se and/or Te) and the hydrochalcogenide anions, HCh-, have been prepared and characterized in solution by 1H, 77Se, 123/s
- Bj?rgvinsson, Már,Schrobilgen, Gary J.
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p. 2540 - 2547
(2008/10/08)
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