- INHIBITION OF OLIG2 ACTIVITY
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Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of Olig2. Also described herein are methods of using such Olig2 inhibitors, alone and in combination with other compounds, for treating cancer and other diseases. In particular the Olig2 inhibitors may be used to treat glioblastoma.
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Paragraph 00323-00324
(2018/03/25)
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- BICYCLO HETEROCYCLIC COMPOUND HAVING ANTIFUNGAL ACTION
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It is intended to provide a 1,6-β-glucan synthase inhibitor which strongly inhibits proliferation and has a high safety. It is intended to provide a compound which can specifically or selectively expressing an antifungal action on a broad spectrum based on the action mechanism of inhibiting the synthesis of 1,6-β-glucan. Further, it is intended to provide a drug, in particular, an antifungal agent containing the above compound, its salt or a hydrate thereof. More specifically speaking, a compound represented by the following general formula (I), its salt or a hydrate thereof; and a drug or an antifungal agent containing the above compound, its salt or a hydrate thereof.
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Page/Page column 172
(2008/06/13)
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- INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE
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Compounds of formula (I) in free or salt form, wherein R1, R2, R3, and R4 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by mediated by phosphatidylinos
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- Indole derivatives as 5-HT1-like agonists for use in migraine
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The present invention relates to 3,5-disubstituted indole compounds which are selective agonists which act on 5-hdroxytryptamine receptors useful in the treatment of migraine.
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