Generation of unnatural α,α-disubstituted amino acid derivatives from cyclic sulfamidates
Cyclic sulfamidates function as excellent precursors to a variety of unnatural α,α-disubstituted amino acid derivatives by ring opening with a suitable nucleophile. Addition of various nucleophiles to a sulfamidate derived from 2-methylserine is described.
Boulton, Lee T.,Stock, H. Thijs,Raphy, Jennifer,Horwell, David C.
p. 1421 - 1430
(2007/10/03)
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