- Preparation method of 3-bromopropionitrile
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The invention discloses a preparation method of 3-bromopropionitrile, wherein the preparation method comprises the following steps: taking acrylonitrile as a raw material, carrying out trimethylbromosilane intermolecular addition reaction, and distilling and purifying to obtain high-purity 3-bromopropionitrile. According to the method, cheap acrylonitrile is used as the raw material, and the high-purity 3-bromopropionitrile is obtained through the trimethylbromosilane intermolecular addition reaction and finally distillation and purification; the raw material is cheap and easy to obtain, and the method is suitable for commercial production, environmentally friendly, small in amount of generated three wastes and high in yield.
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Paragraph 0024; 0026-0032
(2020/03/06)
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- One-pot synthesis of aryl sulfones from alcohols
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A one-pot synthesis of aryl sulfones from primary alcohols is described. Alcohols were treated with N-bromosuccinimide and triphenylphosphine, followed by addition of sodium arenesulfinate with a catalytic amount of tetrabutylammonium iodide to afford the aryl sulfones in good to high yields.
- Murakami, Teiichi,Furusawa, Kiyotaka
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p. 479 - 482
(2007/10/03)
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- The return of the succinimidyl radical
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The aqueous kinetics of the succinimidyl radical, S., has been re-examined in the presence of oxidizable substrates and oxygen. The results indicate a rapid equilibrium between S. and its ring-opened analogue, the β-(isocyanato-carbonyl)ethyl radical, PI.. The equilibrium constant K1 is ca. 10, with k1 ≈ 107 s-1 and k-1 ≈ 106 s-1. The glutarimidyl radical, G., was produced by one-electron reduction of N-chloroglutarimide, GCl. The rate constants of several oxidation and hydrogen abstraction reactions with S. and G. have been determined. Furthermore, halogen abstraction reactions from haloimides by some selected alkyl radicals were also scrutinised. Most striking is the finding that the 2-cyanoethyl radical abstracts Br from SBr ca. 25 times slower than does the ethyl radical. This demonstrates a strong β-effect and rationalises a relatively slow Br abstraction rate by PI. from SBr. While the closure rate of the PI' radical appears to be solvent-insensitive, the ring opening rate of S., k1, is estimated to be ca. 100 times faster in, e.g., CH2Cl2 than in water. This suggests hydrogen-bonded stabilisation of S.. Acta Chemica Scandinavica 1998.
- Merenyi, Gabor,Lind, Johan,Eberson, Lennart
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