Regiospecific synthesis of substituted nitrofluorenes and aminofluorenes with the Negishi coupling reaction as key step
A short regiospecific route to 7-alkyl/CF3 substituted 2-nitrofluorenes and 2-aminofluorenes is described. The synthesis takes advantage of the palladium(0)-catalysed Negishi coupling of methyl 2-bromo-5-nitrobenzoate with aromatic zinc species
Klein,Boche
p. 1246 - 1250
(2007/10/03)
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