- A RAMAN SPECTROSCOPIC STUDY OF THE LOW-FREQUENCY VIBRATIONS OF o-DIMETHOXYBENZENE AND ITS METHYL DEUTERATED ANALOGUES
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The low-frequency (100-400 cm-1) Raman spectra of liquid (at 300 K) and solid (at 130 K) veratrole (o-dimethoxybenzene), and its methyl deuterated analogues, have been measured.The methyl and methoxyl torsional transitions have been identified, and the corresponding rotational barriers have been determined.The interpretation of the spectra points to a conformationally mixed situation for solid veratrole, in which both planar and non-planar conformers may co-exist.
- Konschin, Henrik,Tylli, Henrik,Westermark, Bertel
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- DEUTERATED FORMS AND DERIVATIVES OF VOLINANSERIN
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Deuterated forms of volinanserin according to structural formula (I), and their pharmaceutically acceptable salts, pharmaceutical compositions containing these compounds, and methods of treatment or prevention using these compounds or pharmaceutical compositions are described. The compounds are useful for treating or preventing a disease or condition selected from psychosis, schizophrenia, schizoaffective disorder, Parkinson's disease, Lewy body dementia, sleep disorder (including insomnia), agitation, mood disorder (including depression), thromboembolic disorder, autism, and attention deficit hyperactivity disorder.
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Paragraph 167
(2020/07/14)
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