Syntheses and evaluation of the potentially oestrophilic cytostatics 2,3-epoxy-3,4-bis-(4-acetoxyphenyl)-4-hexene and 2,3,4,5-bisepoxy-3,4-bis-(4-acetoxyphenyl)hexane
Uncertainty concerning the configuration of dienestrol was resolved by a detailed spectrochemical investigation, including single crystal X ray diffraction, of the active drug and its stereoisomers. A symmetric structure in which the phenyl and methyl groups are cis about each double bond is unambiguously assigned.
Doyle,McDonald Stewart,Filipescu,Benson
p. 1525 - 1528
(2007/10/13)
More Articles about upstream products of 24705-61-1