3-Amidinophenylalanine-based inhibitors of urokinase
Synthesis and anti-uPA activity of a series of Nα-triisopropyl-phenylsulfonyl-protected 3-amidino-phenylalanine amides are described. We have explored SAR around the C-terminal amide part for inhibition of uPA, plasmin and trypsin. Modification of the ami
Stuerzebecher, Joerg,Vieweg, Helmut,Steinmetzer, Torsten,Schweinitz, Andrea,Stubbs, Milton T.,Renatus, Martin,Wikstroem, Peter