- Carbacephalosporin compound, their preparation and use
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Carbacephalosporin compounds of formula (I), STR1 salts thereof, processes for their synthesis and uses thereof, wherein: R1 is hydrogen, methoxy or formamido; R2 is an acyl group; CO2 R3 is a carboxy group or a carboxylate anion, or R3 is a carboxy protecting group or a pharmaceutically acceptable salt-forming group or in vivo hydrolysable ester group; R4, R5, R6 and R7 represent hydrogen or a substituent; R4 and R7 may be replaced by a chemical bond between the two carbon atoms shown; R5 and R6 may be linked together into a cyclic system. The compounds (I) have antibacterial properties.
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- BIS (TRIMETHYLSILYL) AMIDE AS NITRILE PRECURSOR
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Bis (trimethylsilyl) amides are converted into nitriles with high yields when they are treated with a catalyst (tetrabutylammonium fluoride, Lewis acids or iron phthalocyanine).
- Rigo, Benoit,Lespagnol, Charles,Pauly, Marc
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p. 347 - 348
(2007/10/02)
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- Bis-trimethylsilyl cefamandole and process therefor
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Bis-trimethylsilyl cefamandole is useful for regenerating cefamandole of excellent purity.
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