Copper-assisted preparation of pyridinyl sulfonate esters from hydroxypyridines and sodium sulfinates
An efficient and powerful copper-assisted method for the effective conversion of a broad range of hydroxypyridines and sodium sulfinates into their corresponding pyridinyl tosylates was developed. Key features of this base- and ligand-free protocol include using the cheap and readily available CuBr2 as a medium and the use of sodium sulfinates as formal sulfonylation reagents. A variety of functional pyridinyl tosylates could be formed with good yields, which can easily be converted into C-C and C-N bond-containing compounds. This journal is
Heteroaromatic tosylates as electrophiles in regioselective Mizoroki-Heck-coupling reactions with electron-rich olefins
Heteroaromatic 2-pyridyl tosylates were successfully applied as electrophiles in palladium(0)-catalyzed Mizoroki-Heck-coupling reactions to electron-rich olefins with complete aregioselectivity. This protocol represents a general strategy for the application of pyridyl tosylates and mesylates in the Mizoroki-Heck coupling. The catalytic system also proved adaptable to changes in the heteroaromatic core as well as large-scale applications. Finally, the synthetic utility of the functionalized α-heteroarylvinyl amides was established providing straightforward access to highly functionalized heteroaromatic compounds including chiral benzylic amide derivatives.
Gogsig, Thomas M.,Lindhardt, Anders T.,Dekhane, Mouloud,Grouleff, Julie,Skrydstrup, Troels
supporting information; experimental part
p. 5950 - 5955
(2010/02/28)
Scope and limitation of the nickel-catalyzed coupling reaction between lithium borates and mesylates
Coupling reaction of aryl borates and mesylates derived from phenols and enols was studied. Mesylates with an electron-with-drawing group or ring were highly reactive at room temperature in the presence of NiCl2(PPh3)2 to furnish the coupling products in good yields.
Kobayashi, Yuichi,William, Anthony D.,Mizojiri, Ryo
p. 91 - 97
(2007/10/03)
Insecticidal compounds and compositions
The invention provides insecticidally active compounds of formula: STR1 wherein X is N or CH; Ra is the group (R1)(R2)NS(O)n --wherein R1 and R2 are independently selected from H, alkyl, ha
-
(2008/06/13)
More Articles about upstream products of 25795-97-5