cas 25823-50-1, 3-CHLORO-5,6-DIHYDRO-BENZO[H]CINNOLINE | Articles data ｜lookchem

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25823-50-1

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SUBSTITUTED TRIAZOLES USEFUL AS AXL INHIBITORS
Substituted triazoles and pharmaceutical compositions containing the compounds are disclosed as being useful in inhibiting the activity of the receptor protein tyrosine kinase Axl. Methods of using the compounds in treating diseases or conditions associated with Axl activity are also disclosed.
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Page/Page column 145-146

(2008/12/07)

PYRIDAZINE COMPOUNDS AND METHODS
The invention relates to novel chemical compounds, compositions and methods of making and using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions comprising the same, and methods of
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Page/Page column 8; 55; 1/7

(2008/06/13)

Synthesis, hypotensive and diuretic activities of several 3-hydrazino-5,6-dihydrobenzo[h]cinnolines. Part 10: Pyridazine derivatives
New 3-hydrazino-5,6-dihydrobenzo[h]cinnolines were prepared, and their effects on arterial pressure, diuresis and Na+ and K+ excretion in conscious normotensive rats were studied.
Ravina,Fueyo,Teran,Cid,Garcia Mera,Orallo,Bardan
p. 574 - 577
(2007/10/02)

More Articles about upstream products of 25823-50-1

25823-49-8
5,6-Dihydrobenzo[h]cinnolin-3(2H)-one

More Articles about downstream products of 25823-50-1

Chemical Properties

Melting Point: 155-156 °C(Solv: ethanol (64-17-5))
Boiling Point: 431.6 °C at 760 mmHg
Flash Point:247.4 °C
Density: 1.317 g/cm³
Vapor Pressure: 2.98E-07mmHg at 25°C
Refractive Index: 1.643
PKA: 1.08±0.20(Predicted)
PSA: 25.78000
LogP: 2.89560

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