Preparation of 14C-labelled 1,4-dideoxy-1,4-imino-D-arabinitol: Cyanosilylation of cyclic imines using KCN in a one-pot synthesis
A new method for C-C bond formation was developed based on in situ cyanosilylation of cyclic Schiff bases using KCN, TMSCl, KI and ZnI2. This method was used to prepare the potent α-glucosidase inhibitor 1,4-dideoxy-1,4-imino-D-arabinitol
Folkersen, Birgitte M.,Lundt, Inge,Foged, Christian,Valsborg, Jacob S.
p. 1145 - 1159
(2007/10/03)
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