- AZAPHENOTHIAZINES AND AZAPHENOXAZINES AS ANTIOXIDANTS
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The present disclosure relates generally to antioxidants. More particularly, the present disclosure relates to lubricating compositions comprising an antioxidant.
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Paragraph 00125
(2018/10/24)
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- COMPOUND, ORGANIC LiGHT EMITTING DIODE INCLUDING THE SAME, COMPOSITION INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LiGHT EMITTING DIODE
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The present invention relates to a compound, an organic light emitting diode including the same, a composition for the organic light emitting diode including the same, and a display device comprising the organic light emitting diode. The present invention is to provide a compound which can provide an organic photoelectron diode having high efficiency and long service life. To this end, provided is a compound for an organic photoelectron diode represented by chemical formula 1.
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Paragraph 0197; 0204-0205
(2016/10/09)
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- Synthesis and antimicrobial activity of novel bis-azaphenothiazines
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N-alkylation of azaphenothiazines using dibromoalkanes or dibromoalkenes did not result in the formation of bis-azaphenothiazines under known conditions such as refluxing, for more than 100 h, with NaNH2/xylene or NaH/toluene. However, when the same reaction was tried with NaH/DMF at -5 C to r.t., it yielded the desired product in 68-71 % yield. These novel bis-azaphenothiazines containing a suitable alkyl or alkenyl spacer were found to possess moderate to significant antimicrobial activities against three gram positive bacteria (Staphylococcus aureus, Bacillus subtilis, and Staphylococcus epidermis), four gram negative bacteria (Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, and Klebsiella pneumoniae) as well as four fungi (Aspergillus niger, Aspergillus fumigatus, Aspergillus flavus, and Candida albicans). Compounds 2b-d were found to exhibit strong antifungal activity, comparable to the standard drug miconazole against A. niger and A. fumigatus.
- Kushwaha, Khushbu,Sakhuja, Rajeev,Jain, Subhash C.
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p. 4459 - 4467
(2013/09/02)
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- Synthesis and antitubercular activity of phenothiazines with reduced binding to dopamine and serotonin receptors
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Analogs of the psychotropic phenothiazines were synthesized and examined as antitubercular agents against Mycobacterium tuberculosis H37Rv. The compounds were subsequently counter-screened for binding to the dopaminergic-receptor subtypes D1, D2, D3 and the serotonergic-receptor subtypes 5-HT1A, 5-HT2A, and 5-HT2C. The most active compounds showed MICs from 2 to 4 μg/mL and had overall reduced binding to the dopamine and serotonin receptors compared to chlorpromazine and trifluoperazine.
- Madrid, Peter B.,Polgar, Willma E.,Toll, Lawrence,Tanga, Mary J.
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p. 3014 - 3017
(2008/02/07)
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- New Synthesis of 4-Azaphenothiazine
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The reaction of 2-chloropyridine with 2-aminothiophenol gives N-(2-mercaptophenyl)-2-pyridinamine (2) which is cyclised to give 4-azaphenothiazine (3), a useful intermediate for pharmaceuticals.An improved one-pot synthesis is reported and a reaction mechanism proposed. - Key Words: Azaphenothiazine / Smiles rearrangement / Pyridobenzothiazine
- Kutscher, Bernhard,Dieter, Hans Reinhold,Troemer, Hans-Guenther,Bartz, Beate,Engel, Juergen,Kleemann, Axel
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p. 591 - 592
(2007/10/02)
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