Copper-catalyzed electrophilic amination of sodium sulfinates at room temperature
By using O-benzoyl hydroxylamines as amine sources, the first convenient copper-catalyzed electrophilic amination of sodium sulfinates has been realized. Even with 2 mol% catalyst loading, the protocol provided an efficient and straightforward synthesis of a broad range of functional sulfonamides under ambient reaction conditions without an additional base and ligand. Based on the control experiments, a plausible mechanism was proposed.
Zhu, Haibo,Shen, Yajing,Deng, Qinyue,Tu, Tao
supporting information
p. 16573 - 16576
(2015/11/18)
A general and mild two-step procedure for the synthesis of aryl and heteroaryl sulfonamides from the corresponding iodides
A mild two-step preparation of aryl and heteroaryl sulfonyl chlorides and sulfonamides from their corresponding iodides is developed. Acid labile functionalities are shown to be stable under both the copper-catalysed coupling and the subsequent oxidative chlorination.
Ho, Danny K.H.,Chan, Lily,Hooper, Alice,Brennan, Paul E.
p. 820 - 823
(2011/03/18)
Acetyl-CoA carboxylase inhibitors
Acetyl Coenzyme A Carboxylase inhibitors, pharmaceutical compositions containing such compounds and the use of such compounds to treat for example, Metabolic Syndrome including atherosclerosis, diabetes and obesity.
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(2008/06/13)
Regioselective Lithiation of 3-Pyridylsulfonic Acid Derivatives: A Convenient Route to Various New 4-Substituted 3-Pyridylsulfonamides
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Breant, P.,Marsais, F.,Queguiner, G.
p. 822 - 824
(2007/10/02)
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