- Synthesis method of 3-oxetanone
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The invention discloses a synthesis method of 3-oxetanone. Specifically, 1, 3-dichloroacetone and ethylene glycol are taken as raw materials, 3-oxetanone is synthesized at high yield through three steps of carbonyl protection reaction, ring closing reaction and deprotection reaction. The preparation method of 3-oxetanone is a synthesis method which is high in yield, low in cost, environment-friendly, easy to operate and suitable for industrialization.
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Paragraph 0040-0043; 0048-0051; 0056-0059
(2020/11/25)
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- Method for preparing 1,3-dihydroxyacetone from 1,3-dichloroacetone
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The invention discloses a method for preparing 1,3-dihydroxyacetone from 1,3-dihydroxyacetone. The method comprises the following steps: by taking 1,3-dichloroacetone and ethylene glycol as raw materials and taking p-toluenesulfonic acid as a catalyst, reacting at the temperature of 0-110 DEG C so as to produce 1,3-dichloroacetone ethylene ketal; adding sodium hydroxide of a certain mass fraction, and hydrolyzing under alkaline conditions so as to obtain 1,3-dihydroxyacetone ethylene ketal; and finally, adding sulfuric acid for acidifying so as to enable the solution to be acidic, obtaining a mixture containing dihydroxyacetone and ethylene glycol, desalting the mixture, evaporating, concentrating, recrystallizing, and filtering, thereby obtaining the dihydroxyacetone crystal, wherein the filtrate is a mixed solution containing sodium sulfate, and the yield of the dihydroxyacetone can reach 60% or higher. The method disclosed by the invention can be used for an industrial production path of dihydroxyacetone, and has the advantages of high yield, low cost, simplicity in operation and separation and the like compared with a biological method, and is convenient for industrial production.
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Paragraph 0036-0037
(2017/08/29)
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- Electrosynthesis of cyclopropanone adducts
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Electroreduction of α, α'-dihalo ketones to cyclopropanones (isolated as the hemiacetals or hemiacylals) is accomplished with good yields only with highly alkylated α, α'-dihalo ketones.Attempts to prepare little substituted or unsubstituted cyclopropanon
- Tilborg, W. J. M. van,Plomp, R.,Ruiter, R. de,Smit, C. J.
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p. 206 - 212
(2007/10/02)
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