- Constituents of Sindora sumatrana MIQ. I. Isolation and NMR spectral analysis of sesquiterpenes from the dried pods
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Investigation of the neutral fraction of the dried pods of Sindora sumatrana MIQ. has resulted in the isolation of three new sesquiterpenoids (2, 6 and 8) together with nine known ones (1, 3, 4, 5, 7, 9, 10, 11a and 12a), of which three (7, 10 and 12a) are reported for the first time from a natural source. One other compound, 4-stigmasten-3-one (13) (together with a sterol mixture; β-sitosterol, stigmasterol and campesterol) was also obtained. The structures of all the isolated sesquiterpenes were determined by means of spectroscopic methods, mainly two-dimensional NMR techniques, and the compounds were found to have the caryophyllane, humulane, clovane and caryolane skeletons. The NMR data of the isolated sesquiterpenes are also discussed.
- Heymann,Tezuka,Kikuchi,Supriyatna
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p. 138 - 146
(2007/10/02)
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- Constituents of Sindora sumatrana MIQ. II. Five new sesquiterpenoids from the dried pods
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Further investigation of the neutral fraction of the methanolic extract of Sindora sumatrana MIQ. (Leguminosae) has yielded five new sesquiterpenoids: a new trans-isodaucane diol (1), two caryophyllane-type epoxydiols (2, 3), the diacetate of a caryophyllane-type trialcohol (4) and a caryolane-type hydroxy-ketone (5) which possesses an α-C-12 methano bridge. The structure elucidation of the compounds was based mainly on two-dimensional NMR techniques. The biosynthetic significance of the acid-catalyzed rearrangement of 5 to give a clovane-type hydroxyketone (10) is also discussed.
- Heymann,Tezuka,Kikuchi,Supriyatna
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p. 941 - 946
(2007/10/02)
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