cas 265312-60-5, 4,7-Benzothiazoledione,5-methoxy-2-methyl-(9CI) | Articles data ｜lookchem

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265312-60-5

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Benzimidazole- and benzothiazole-quinones: Excellent substrates for NAD(P)H:quinone oxidoreductase 1
A series of benzimidazole- and benzothiazole-quinones has been synthesized. The ability of these heterocyclic quinones to act as substrates for recombinant human NAD(P)H:quinone oxidoreductase (NQO1), a two-electron reductase upregulated in tumour cells,
Newsome, Jeffery J.,Colucci, Marie A.,Hassani, Mary,Beall, Howard D.,Moody, Christopher J.
p. 3665 - 3673
(2008/09/21)

Synthesis and biological evaluation of novel heterocyclic quinones as inhibitors of the dual specificity protein phosphatase CDC25C
A focused set of heterocyclic quinones based on the benzothiazole, benzoxazole, benzimidazole, indazole and isoindole was prepared and screened with respect to the inhibition of the phosphatase activity of CDC25C. Benzoxazole- and benzothiazole-diones wer
Lavergne, Olivier,Fernandes, Anne-Cecile,Brehu, Laetitia,Sidhu, Alban,Brezak, Marie-Christine,Prevost, Gregoire,Ducommun, Bernard,Contour-Galcera, Marie-Odile
p. 171 - 175
(2007/10/03)

5-Arylamino-2-methyl-4,7-dioxobenzothiazoles as inhibitors of cyclin-dependent kinase 4 and cytotoxic agents
5-Arylamino-2-methyl-4,7-dioxobenzothiazoles were synthesized as inhibitors of cyclin-dependent kinase 4 (CDK4) and cytotoxic agents. Most of the 4,7-dioxobenzothiazoles exhibited selective inhibitory activities for the CDK4 and cytotoxic potential agains
Ryu, Chung-Kyu,Kang, Hye-Young,Lee, Sang Kook,Nam, Kyung Ae,Hong, Chang Yong,Ko, Won-Gil,Lee, Byung-Hoon
p. 461 - 464
(2007/10/03)

More Articles about upstream products of 265312-60-5

265312-59-2
4-amino-5-methoxy-2-methylbenzothiazole

Chemical Properties

Melting Point: 255 °C (decomp)(Solv: dichloromethane (75-09-2); pentane (109-66-0))
Boiling Point: 380.4±42.0 °C(Predicted)
Density: 1.43±0.1 g/cm3(Predicted)
Storage Temp.:2-8°C
PKA: -2.36±0.20(Predicted)
PSA: 84.50000
LogP: 1.36080

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