- Design, synthesis, and application of enantioselective coupling reagent with a traceless chiral auxiliary
-
(Chemical Equation Presented) Stable chiral N-triazinylbrucinium tetrafluoroborate enantioselectively activates racemic carboxylic acids yielding enantiomerically enriched amides, esters, and dipeptides with er from 8:92 to 0.5:99.5. Due to the departure
- Kolesinska, Beata,Kaminski, Zbigniew J.
-
supporting information; experimental part
p. 765 - 768
(2009/09/06)
-
- Synthesis and antitumor activity of cyclodepsipeptide zygosporamide and its analogues
-
The synthesis and structure-activity relationships of zygosporamide, a known potent and selective cytotoxic natural product against SF-268 and RXF 393 cell lines, are described. The potencies of the synthetic zygosporamide are similar to those reported fo
- Wang, You,Zhang, Feiran,Zhang, Yihua,Liu, Jun O.,Ma, Dawei
-
scheme or table
p. 4385 - 4387
(2009/04/06)
-
- SYNTHESIS OF BIOLOGICALLY ACTIVE ANALOGS OF LULIBERIN WITH SHORTENED AMINO ACID SEQUENCES
-
Two new analogs of the releasing factor of the luteinizing hormone with shortened amino acid sequences have been synthesized by the methods of classical peptide chemistry.The influence of the preparations on the action of chorionic gonadotropin and on the
- Burov, S. V.,Nikolaev, S. V.,Smironova, M. P.,Lupanova, G. E.,Bobrov, Yu. F.,et al.
-
p. 732 - 737
(2007/10/02)
-
- SYNTHESIS OF 3(NH2); Pro3; D-Ala6>- and 2(NO2); Pro3; D-Ala6>LULIBERINS
-
In order to study the influence of substituents of the aromatic ring of D-phenylalanine on the inhibiting capacity of luliberian analogs, we have synthesized two new analogs: 2; Pro3; D-Ala6>- and
- Burov, S. V.,Kaurov, O. A.,Martynov, V. F.,Smirnova, M. P.
-
p. 518 - 524
(2007/10/02)
-
- Octapeptides and methods for their production
-
New octapeptides having the formula Prot Grp-R-Trp-Ser-Tyr-R2 -Leu-Arg-Pro-R3 ; salts thereof; wherein R is Gln, Gln (bzl), His (bzl), Ser (bzl), Pro, Leu, Tyr (bzl), Ile, Cys (bzl) or Phe, R2 is D-Phe, D-Ala, D-Leu, D-Trp, D-Tyr, D-Tyr (Me), D-Ser, D-Met, D-Arg, D-Val, D-His, D-Gln, D-Phs, D-Thr, D-Pro, D-Me5 Phe or D-Asn and R3 is NH2, NH(lower alkyl), N-(lower alkyl)2, NH-benzyl, NHCH2 CH2 N-(lower alkyl)2 or NH-CH2 CH2 SO2 NH-benzyl; methods for their production; certain peptide intermediates and their salts used in the production thereof; and the use of said octapeptides as luteinizing hormone releasing factor antagonists.
- -
-
-
- Hexapeptides and methods for their production
-
New hexapeptides having the formula X-Ser(benzyl)-Tyr(benzyl)-Ala-Leu-Arg-Pro-Y wherein X is t-butoxycarbonyl or benzyloxycarbonyl and Y is lower alkoxy, amino, lower alkylamino or di(lower alkyl)amino.
- -
-
-
- New pentapeptides and methods for their production
-
New pentapeptides having the formula X-R-Ser-(benzyl)-Tyr(benzyl)-R1 -Y wherein X is t-butoxycarbonyl or benzyloxycarbonyl, R is a single amino acid fragment or a dipeptide fragment utilizing amino acids selected from the group consisting of Az
- -
-
-