- 2,3-DIHYDRO-IMINOISOINDOLE DERIVATIVES
-
A compound represented by the following general formula (1), or a salt thereof has serine protease inhibiting activity, and particularly excellent inhibiting activity against clotting factor VIIa. This compound or a salt thereof is useful as therapeutic and/or prophylactic agents for diseases associated with thrombus formation. [wherein R1 represents hydrogen, R2 represents optionally substituted phenyl, etc., R3 represents optionally substituted C6-10 aryl, etc.]
- -
-
Page/Page column 27
(2009/10/31)
-
- 1,3-THIAZOLE-5-CARBOXAMIDES USEFUL AS CANCER CHEMOTHERAPEUTIC AGENTS
-
This invention relates to novel 1, 3- thiazole-5 -carboxamide compounds of formula (I), pharmaceutical compositions containing such compounds, and the use of those compounds or compositions as cancer chemotherapeutic agents.
- -
-
Page/Page column 30-31
(2008/06/13)
-
- BICYCLIC PYRIMIDIN-4-(3H)-ONES AND ANALOGUES AND DERIVATIVES THEREOF WHICH MODULATE THE FUNCTION OF THE VANILLOID-1 RECEPTOR (VR1)
-
Compounds of formula (I); which are useful as therapeutic compounds, particularly in the treatment of pain and other conditions ameliorated by the modulation of the function of the vanilloid-1 receptor (VR1).
- -
-
Page/Page column 42
(2010/02/12)
-
- -
-
N-cyano, N-acyl and N-ethoxycarbonyl imidates are well known as versatile reagents in the synthesis of heterocyclic compounds. These imidates react with alkyl mercaptoacetates, in basic medium, to lead to the formation of 4-amino-5-alcoxycarbonylthiazoles
- Dridi, Khaireddine,El Efrit, Mohamed Lotfi,Zantour, Hedi
-
p. 407 - 412
(2007/10/03)
-